CLINICAL REVIEW Managing drug resistant tuberculosis
نویسندگان
چکیده
Antituberculosis drug resistance is increasing both in theUnitedKingdomand internationally. 2 It has come to greater public attention with the emergence of extensively drug resistant tuberculosis (box 1) in South Africa, where an outbreak proved rapidly fatal among peoplewith advancedHIV infection. In this articlewe review recent global and UK trends in drug resistant tuberculosis and summarise its diagnosis, treatment, and control. Few data are available from randomised controlled trials to guide treatment of drug resistant tuberculosis, and none for multidrug resistant tuberculosis; this review is based primarily on data from observational epidemiological studies and on national and international guidelines.
منابع مشابه
A 10-year survey on prevalence and occurrence rate of multi-drug resistant Mycobacterium tuberculosis in Latin American and Mediterranean Families: A Systematic review and meta-analysis
Introduction: Latin American and Mediterranean (LAM) is a family of Mycobacterium tuberculosis (M. tuberculosis). Drug resistant in M. tuberculosis LAM family is a major problem in the world population. Our objective of this study was to determine the prevalence of M. tuberculosis LAM family with multi-drug resistant (MDR) in the worldwide by a meta-analysis and systematic review. Materials an...
متن کاملClinical trials on silver nanoparticles for wound healing (review)
Despite the prevalence of different kinds of wounds among people around the world, challenges ahead for managing wound healing continues. One of the most important issues for wound healing is infection that can delay healing process. Also, drug-resistant infections are growing as a worrying challenge in medicine. A lot of studies done over different methods to improve wound healing process, whi...
متن کاملMultidrug-resistant and extensively drug-resistant tuberculosis: a review of current concepts and future challenges.
Multidrug-resistant and extensively drug-resistant tuberculosis are recent global health issues, which makes tuberculosis - after the success of short course treatment during the second half of the last century - a major health challenge. Globalisation, health inequalities, competing economic interests and political instability contribute substantially to the spread of drug-resistant strains, w...
متن کاملAuthor's response to reviews Title: Genotyping and clinical characteristics of multidrug and extensively drug-resistant tuberculosis from a tertiary care tuberculosis hospital in China Authors:
Title: Genotyping and clinical characteristics of multidrug and extensively drug-resistant tuberculosis from a tertiary care tuberculosis hospital in China
متن کاملتشخیص موتاسیون در کدون 315 ژن katG، مارکر مقاومت به ایزونیازید در سوش‌های مایکوباکتریوم توبرکولوزیس جدا شده از بیماران اصفهان و تهران با روش PCR-RFLP
Background and Objective: Drug resistance to tuberculosis is continuously increasing and is a significant threat to tuberculosis control programs because afew effective drugs are present against Mycobacterium tuberculosis. Although isoniazid (INH) is the most effective drug against tuberculosis, resistance to this drug also develops readily. Mutations in katG, specially the Ser315Thr substituti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2008